Mother, Fetal and Disease History Factors as a Preeklampsia Risk in Asia and Africa: A Meta-Analysis
Abstract
Background: Preeclampsia accounts for nearly 10 percent of maternal deaths in Asia and Africa. Therefore, it is important to detect signs and symptoms early on by knowing the factors that are at risk for a mother experiencing preeclampsia. Objective: To determine the risk factors for preeclampsia in Asia and Africa through the application of meta-analysis. Method: A systematic review was carried out on 26 case-control and cohort studies related to risk factors for preeclampsia from four databases (PubMed, BioMed Central, ProQuest, and Google Scholar). The pooled odds ratio was calculated with the fixed-effect and random-effect model using Review Manager 5.3. Result: A total of 20 studies consisting of 2,954,769 women were included in the meta-analysis. Risk factors for preeclampsia based on maternal factors were chronic hypertension=9.74(95% CI 1.69-56.04), gestational diabetes=9.28(95% CI 4, 49-19.19), pre-pregnancy body mass index=2.70(95% CI 2.08-3.50), maternal age during pregnancy=2.37(95% CI 2.29-2.46) and nulliparity=2.08(95% CI 1.44-3.01). The fetal factor was multiple pregnancy=4.24(95% CI 3.14-5.73). Four disease history factors were family history of preeclampsia=13.99(95% CI 6.91-28.33), history of chronic hypertension=8.28(95% CI 5.92- 11.59), history of preeclampsia=OR 6.90(95% CI 3.58-13.31) and family history of hypertension=2.81(95% CI 1.75-4.50). Conclusion: The results of a meta-analysis of 10 risk factors for preeclampsia could be used as a screening tool to determine the magnitude of risk and early diagnosis of preeclampsia that allows timely intervention.
References
Eleni Tsigas. World Preeclampsia Day: Reducing Preventable Deaths From Preeclampsia – Maternal Health Task Force [Internet]. MHTF Blog. 2017. Available from:https://www.mhtf.org/2017/05/22/world-preeclampsia-day-reducing-preventable-deaths-from-preeclampsia/
World Health Organization. Prevention and treatment of pre-eclampsia and eclampsia. 2011.
Afifah T, Tejayanti T, Saptarini I, Rizkianti A, Usman Y, Senewe FP, et al. Maternal Death in Indonesia: Follow-up Study of the 2010 Indonesia Population Census. 2016;1–13.
Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel J, et al. Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health. RCOG. 2014;14–24. DOI: 10.1111/1471-0528.12629.
Cripe SM, O’Brien W, Gelaye B, Williams MA. Perinatal outcomes of Southeast Asians with pregnancies complicated by gestational diabetes mellitus or preeclampsia. J Immigr Minor Heal. 2012;14(5):747–53. DOI: 10.1007/s10903-011-9537-7.
Dawson LM, Parfrey PS, Hefferton D, Dicks EL, Cooper MJ, Young D, et al. Familial risk of preeclampsia in Newfoundland: A population-based study. J Am Soc Nephrol. 2002;13(7):1901–6. DOI: 10.1097/01.ASN.0000017224.24670.82.
Valadan M, Tanha FD, Sepahi A. Pregnancy Outcomes in Women of Advanced Age. J Fam Reprod Heal. 2011;5(2):57–62.
Bodnar LM, Catov JM, Klebanoff MA, Ness RB, Roberts JM. Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology. 2007;18(2):234–9. DOI: 10.1097/01.ede.0000254119.99660.e7.
Bodnar LM, Ness RB, Markovic N, Roberts JM. The risk of preeclampsia rises with increasing prepregnancy body mass index. Ann Epidemiol. 2005;15(7):475–82. DOI: 10.1016/j.annepidem.2004.12.008
O’Brien TE, Ray JG CW. Maternal Body Mass Index and the Risk of Preeclampsia: A Systematic Overview. Vol. 14, Epidemiology. 2003.
Sohlberg S, Stephansson O, Cnattingius S, Wikström AK. Maternal body mass index, height, and risks of preeclampsia. Am J Hypertens [Internet]. 2012;25(1):120–5. Available from: http://dx.doi.org/10.1038/ajh.2011.175/nat ure06264
Wang Z, Wang P, Liu H, He X, Zhang J. Maternal adiposity as an independent risk factor for pre-eclampsia: A meta-analysis of prospective cohort studies. Obes Rev. 2013;14(6):508–21. DOI: 10.1111/obr.12025.
Jeyabalan A. Epidemiology of preeclampsia: impact of obesity. Nutr Rev [Internet]. 2013;71 Suppl 1(0 1):S18-25. DOI: 10.1111/nure.12055.
Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: Systematic review of controlled studies. Br Med J. 2005;330(7491):565–7. DOI: 10.1136/bmj.38380.674340.E0.
Wahyudi, S., & Pangestuti, I. R. D. Managing The Pension Fund To Improve Portfolio Performance: An Empirical Study On Employer Pension Funds In Indonesia.
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